Glutamic Acid Independent Production of Poly(γ-glutamic acid) byBacillus subtilisTAM-4

Microbial production of poly-γ-glutamic acid.

Poly-γ-glutamic acid (γ-PGA) is a natural, biodegradable and water-soluble biopolymer of glutamic acid. This review is focused on nonrecombinant microbial production of γ-PGA via fermentation processes. In view of its commercial importance, the emphasis is on L-glutamic acid independent producers (i.e. microorganisms that do not require feeding with the relatively expensive amino acid L-glutami...

Glutamic Acid Dehydrogenase and Glutamic-oxalacetic

As part of a larger project dealing with an in vestigation of amino acid and protein metabolism in leukemia, a study was undertaken to determine those enzymes concerned with amino acid anabo lism and catabolism as they occur in selected tis sues. Several review papers (@,4, 11, 1@)have ade quately summarized our present knowledge of the metabolism of white blood cells (WBC) in leuke mia. Howeve...

Determination of Glutamic Acid

Glutamic Acid Independent Production TAM - 4 of Poly ( 7 - glutamicacid ) by Bacitlas subtilis

A bacterium that produced a large amount of poly(v-g]utamic acid) (PGA) when it was grown aerobically in a culture medium containing ammonium salt and sugar as sollrces of nitrogen and carbon, respectiyely, was isolated from soil. The bacterium, strain TAM-4, was classified as Bacillits nbtilis. The maximum PGA production (22.1 mglm}) was ebtained when it was grown in a medium containing 1.8% a...

Differential Presentation of Glutamic Acid